G - Physics – 01 – N
Patent
G - Physics
01
N
167/45, 195/1.11
G01N 33/573 (2006.01) C07K 16/38 (2006.01)
Patent
CA 1320682
PATENT CL-135A Abstract of the Disclosure The present invention relates to the discovery that elastase inactivates antithrombin III (AT-III) in vivo and that such inactivation produces an inactivated form of AT-III, termed ATx, which is not normally present in the circulation. The presence of elastase modified antithrombin can be used to predict pre-thrombotic as well as thrombotic conditions. Treatment of these conditions can include anticoagulant, fibrinolytic, and anti-elastase therapy.
559743
Jordan Robert E.
Nelson Richard M.
Miles Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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