Diagnostic radio-labeled polysaccharide derivatives

Details Diagnostic radio-labeled polysaccharide derivatives Diagnostic radio-labeled polysaccharide derivatives

C - Chemistry, Metallurgy

08

B

260/210

C08B 37/00 (2006.01) A61K 51/06 (2006.01) C08B 37/10 (2006.01)

Patent

CA 1177072

Abstract of the Disclosure A novel class of chelated radio-labeled polysaccharide derivatives are useful far diagnosing formed, and forming, blood clots in a vascular system. Novel intermediate metal-binding compounds comprise a water-soluble polysaccharide moiety having an average of at least 0.25 anionic groups per monosaacharide unit, and at least one chelating group derived from amino acids, substituted cyclic acid anhydrides, or carbon disulfide. The intermediate compound is then reacted with a radioactive tracer metal compound.

391590

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