Diagnostic test for inflammatory endothelial dysfunctions in...

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G01N 33/68 (2006.01)

Patent

CA 2632952

The present invention relates to a diagnostic test for inflammatory endothelial dysfunctions in pregnant women. Particularly, the present invention relates to a method of diagnosing or evaluating the risk of contracting an inflammatory endothelial dysfunction of the maternal compartment comprising the following steps: a) detecting the plasma levels of long pentraxin PTX3 in blood samples taken from a pregnant woman; b) comparing the PTX3 plasma level data, obtained according to step a) , with statistically significant PTX3 plasma level data of normal pregnant population.

La présente invention concerne un test de diagnostic des dysfonctionnements endothéliaux inflammatoires chez la femme enceinte. En particulier, la présente invention concerne un procédé de diagnostic d'un dysfonctionnement endothélial inflammatoire du compartiment maternel ou d'évaluation du risque de développer celui-ci comprenant les étapes suivantes consistant à : a) détecter les niveaux plasmatiques de la pentraxine longue PTX3 dans des échantillons sanguins prélevés chez une femme enceinte ; b) comparer les données de niveau plasmatique de la PTX3, obtenues à l'étape a), avec des données statistiquement significatives du niveau plasmatique de la PTX3 de la population enceinte normale.

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