Diagnostics and therapeutics for glaucoma

Details Diagnostics and therapeutics for glaucoma Diagnostics and therapeutics for glaucoma

G - Physics

01

N

G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2729889

The invention provides methods and compositions for diagnosing and treating glaucoma by detecting alterations in the Wnt signaling pathway-including changes in the level or bioactivity of frizzled related protein. The invention further provides methods for screening for anti-glaucomatous compounds by detecting a Wnt pathway component such as a frizzled related protein, as well as methods for predicting or diagnosing glaucoma based upon the detection of a genetic alteration in a Wnt pathway component gene.

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