Diagnostics and therapeutics for glaucoma

Details Diagnostics and therapeutics for glaucoma Diagnostics and therapeutics for glaucoma

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A01K 67/027 (2006.01) A61K 39/395 (2006.01) A61P 27/06 (2006.01) C07K 14/47 (2006.01) C12N 9/00 (2006.01) C12N 9/12 (2006.01) C12N 15/00 (2006.01) C12Q 1/48 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2401775

This invention provides methods and compositions for diagnosing and treating glaucoma based on determining the level of a Frizzle Related Protein (FRP), a component of the wingless (Wnt) signaling pathway. The method can include the detection of a genetic lesion like polymorphic allele (e.g. FRP promoter, ...) for diagnosing glaucoma. This invention also discloses the use of transgenic animals for the study of glaucoma (screening for therapeutics, animal disease model, ...).

La présente invention concerne des procédés et compositions convenant au diagnostic et au traitement du glaucome.

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