Diamines as modulators of chemokine receptor activity

Details Diamines as modulators of chemokine receptor activity Diamines as modulators of chemokine receptor activity

C - Chemistry, Metallurgy

07

C

C07C 237/22 (2006.01) A61K 31/165 (2006.01) A61K 31/33 (2006.01) A61P 9/00 (2006.01) A61P 11/06 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) C07C 237/36 (2006.01) C07C 271/28 (2006.01) C07C 275/42 (2006.01) C07D 209/14 (2006.01) C07D 213/64 (2006.01) C07D 295/185 (2006.01) C07D 295/215 (2006.01) C07D 317/58 (2006.01) C07D 317/60 (2006.01) C07K 5/02 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2432908

The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.

La présente invention concerne des modulateurs des MCP-1 représentés par la formule générale (I), ou certaines de leurs formes salines pharmaceutiquement admises. Ces modulateurs conviennent pour la prévention de l'asthme, de la sclérose en plaques, de l' athérosclérose et de la polyarthrite rhumatoïde.

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