C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
260/19
C07J 43/00 (2006.01) C07J 13/00 (2006.01) C07J 41/00 (2006.01) C07J 71/00 (2006.01)
Patent
CA 1084044
ABSTRACT OF THE DISCLOSURE This invention relates to compounds of the general formula Image I and acid addition salts thereof wherein Ac is an alkyl carbonyl group containing 1 to 4 carbon atoms in the alkyl moiety and one of R1 and R?, is a methylene group and the other is a group of the general formula ?N-R2 wherein R2 is an alkyl group containing 1 to 3 carbon atom - n is 1 or 2, m is 1, 2, 3 or 4, and quaternary salts thereof of the general formulae Image Ia and Image Ib wherein Ac, R1 and n and m have the same meanings as defined above and A is halogen and R3 is an alkyl group containing 1 to 4 carbon atoms, or an allyl group. This invention also relates to a process for the preparation of such compounds. The compounds of this invention exhibit activity of the curave type i.e. they show a non-depolarizing neuromuscular blocking effect.
258056
Biro Katalin
Karpati Egon
Marsai Maria
Szeberenyi Szabolcs
Szporny Laszlo
Fetherstonhaugh & Co.
Richter Gedeon Vegyeszeti Gyar Rt
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