Diaminopyrimidinecarboxamide derivative

Details Diaminopyrimidinecarboxamide derivative Diaminopyrimidinecarboxamide derivative

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61K 31/55 (2006.01) A61K 31/551 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 43/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 453/02 (2006.01) C07D 471/08 (2006.01) C07D 471/10 (2006.01)

Patent

CA 2490888

A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided. A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2--position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.

Composé qui peut être utilisé dans la prévention et/ou le traitement des maladies respiratoires auxquelles participe STAT 6, notamment l'asthme, les maladies pulmonaires obstructives chroniques, etc. Le composé est soit un dérivé de pyrimidine comportant en deuxième position un groupe arylamino ou aryléthylamino éventuellement substitué par un substitutif déterminé, en cinquième position un groupe aminé substitué par benzyle, etc., et un groupe carbamoyle éventuellement substitué en cinquième position soit un sel dudit dérivé.

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