Diaminopyrimidines as p2x3 and p2x2/3 modulators

Details Diaminopyrimidines as p2x3 and p2x2/3 modulators Diaminopyrimidines as p2x3 and p2x2/3 modulators

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/506 (2006.01) A61P 11/00 (2006.01) A61P 13/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2620129

Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the compounds being of formula (I) wherein D, X, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.

La présente invention concerne des composés et des procédés de traitement de maladies facilitées par un P2X3 et/ou un antagoniste du récepteur P2X2/3, les composés étant de formule (I) où D, X, R1, R2, R3, R4, R5, R6, R7 et R8 sont définis ici.

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