Diaminopyrroloquinazolines compounds as protein tyrosine...

Details Diaminopyrroloquinazolines compounds as protein tyrosine... Diaminopyrroloquinazolines compounds as protein tyrosine...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2524709

This Invention relates to diaminopyrroloquinazoline compounds of formula (I) wherein R1, R2, R3, Ra, Rb, Rc, Rd, Re, Rf and A are as defined in the description and Claims, which are useful for inhibiting protein tyrosine phosphatases, particularly PTP1B, and are useful for lowering blood glucose concentrations in mammals.

Composés diaminopyrroloquinazoline de formule (I) dans laquelle R1, R2, R3, Ra, Rb, Rc, Rd, Re, Rf et A sont tels que définis dans le descriptif et dans les revendications, qui sont utiles pour inhiber les protéine tyrosine phosphatases, en particulier la PTP1B, et pour abaisser le taux de glucose sanguin chez des mammifères.

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