Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses...

C - Chemistry – Metallurgy – 07 – C

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C07C 237/28 (2006.01) A61K 31/166 (2006.01) A61K 31/18 (2006.01) A61K 31/44 (2006.01) A61P 3/04 (2006.01) C07C 311/08 (2006.01) C07D 209/44 (2006.01) C07D 213/24 (2006.01) C07D 231/12 (2006.01) C07D 235/26 (2006.01) C07D 277/28 (2006.01) C07D 295/20 (2006.01) C07D 307/00 (2006.01) C07D 311/58 (2006.01) C07D 317/32 (2006.01)

Patent

CA 2669311

Compounds of Formula (I) that act as antagonists at the mu, kappa and/or delta opioid receptors and therefore useful in the treatment of diseases, conditions and/or disorders that benefit from such antagonism in animals are described herein. Formula (I) where R, R1, R2a, R2b, R3, R4, V, R6, R7, R8, R9, W and X are described herein.

La présente invention concerne des composés répondant à la formule (I) qui agissent en tant qu'antagonistes au niveau des récepteurs mu, kappa et/ou delta opioide et sont de ce fait utiles dans le traitement de maladies, de conditions et/ou de troubles qui bénéficient d'un tel antagonisme chez des animaux. Formule (I) dans la quelle R, R1, R2a, R2b, R3, R4, V, R6, R7, R8, R9, W et X sont décrits dans la présente description.

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