Diaryl ethers as opioid receptor antagonist

Details Diaryl ethers as opioid receptor antagonist Diaryl ethers as opioid receptor antagonist

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/166 (2006.01) A61K 31/44 (2006.01) A61K 31/455 (2006.01) A61K 31/4965 (2006.01) A61K 31/497 (2006.01) A61P 3/04 (2006.01) C07C 235/46 (2006.01) C07D 213/38 (2006.01) C07D 213/643 (2006.01) C07D 213/78 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 217/04 (2006.01) C07D 237/24 (2006.01) C07D 241/24 (2006.01) C07D 307/14 (2006.01) C07D 333/20 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 41

Patent

CA 2499690

A compound of the formula (I) wherein the variables X1 to X10, R1 to R7 including R3', E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed.

L'invention concerne un composé de formule (I), dans laquelle les variables X¿1? à X¿10?, R?1¿ à R?7¿ comprennent R?3'¿, E, v, y, z, A et B sont tels que définis dans la description ou représentent un sel pharmaceutiquement acceptable, un solvate, un énantiomère, un racémate, un diastéréomère ou un de leurs mélanges. Ledit composé est utilisé dans le traitement, la prévention ou l'amélioration de l'obésité et des maladies associées.

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