Diaryl piperidines as cb1 modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/18 (2006.01) C07D 211/26 (2006.01) C07D 211/28 (2006.01) C07D 211/32 (2006.01) C07D 211/76 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 413/06 (2006.01) C07D 413/12 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2637057

A compound having the general structure of Formula (I): or a pharmaceutically acceptable salt, solvate, or ester thereof, are useful in treating diseases, disorders, or conditions such as metabolic syndrome (e.g., obesity, waist circumference, lipid profile, and insulin sensitivity), neuroinflammatory disorders, cognitive disorders, psychosis, addictive behavior, gastrointestinal disorders, and cardiovascular conditions.

L'invention concerne des composés de formule (I), ou un sel de qualité pharmaceutique, un solvate, ou un ester de ceux-ci, utilisés dans le traitement des maladies, des troubles ou des états pathologiques tels que le syndrome métabolique (par exemple, l'obésité, le tour de taille, le profil lipidique et la sensibilité à l'insuline), les troubles neuroinflammatoires, les troubles cognitifs, la psychose, le comportement de dépendance, les troubles gastrointestinaux ainsi que les affections cardiovasculaires.

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