C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/47 (2006.01) A61K 31/505 (2006.01) A61P 35/00 (2006.01) C07D 239/34 (2006.01) C07D 403/12 (2006.01)
Patent
CA 2546673
The invention relates to the use of diaryl urea derivatives for the manufacture of pharmaceutical compositions for the treatment of RET dependent disorders, especially RET dependent tumor diseases. The invention further relates to novel N-[4-(pyrimidin-4-yloxy)-phenyl]-N~-phenyl-urea derivatives and their use in the treatment of the animal or human body, especially in the treatment of a protein kinase dependent disease, to pharmaceutical compositions comprising such novel N-[4-pyrimidin-4-yloxy)-phenyl]-N~-phenyl- urea derivatives and to the use of such novel N-[4-(pyrimidin-4-yloxy)-phenyl]- N~-phenyl-urea derivatives for the preparation of pharmaceutical compositions for use in the treatment of protein kinase dependent diseases, especially of proliferative diseases, such as tumour diseases.
L'invention concerne l'utilisation de dérivés de diarylurée pour fabriquer des compositions pharmaceutiques destinées au traitement de troubles dépendant de RET, en particulier de maladies tumorales dépendant de RET. L'invention concerne en outre de nouveaux dérivés de N-[4-(pyrimidin-4-yloxy)-phényl]-N'-phényl-urée et leur utilisation pour traiter des animaux ou des êtres humains, en particulier pour traiter une maladie dépendant de protéines kinases, ainsi que des compositions pharmaceutiques comprenant ces nouveaux dérivés de N-[4-(pyrimidin-4-yloxy)-phényl]-N'-phényl-urée et l'utilisation de ces nouveaux dérivés de N-[4-(pyrimidin-4-yloxy)-phényl]-N'-phényl-urée pour préparer des compositions pharmaceutiques destinées à être utilisées en traitement de maladies dépendant de protéines kinases, en particulier de maladies prolifératives, telles que des maladies tumorales.
Bold Guido
Caravatti Giorgio
Floersheimer Andreas
Garcia-Echeverria Carlos
Guagnano Vito
Fetherstonhaugh & Co.
Novartis Ag
LandOfFree
Diaryl urea derivatives in the treatment of protein kinase... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Diaryl urea derivatives in the treatment of protein kinase..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diaryl urea derivatives in the treatment of protein kinase... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1344303