Diarylakanoids having activity as lipoxygenase inhibitors

Details Diarylakanoids having activity as lipoxygenase inhibitors Diarylakanoids having activity as lipoxygenase inhibitors

C - Chemistry, Metallurgy

07

C

167/179, 260/308

C07C 49/20 (2006.01) C07C 45/72 (2006.01) C07C 45/74 (2006.01) C07C 49/248 (2006.01) C07C 49/255 (2006.01) C07C 59/90 (2006.01) C07C 65/38 (2006.01) C07C 205/45 (2006.01) C07D 307/38 (2006.01) C07D 307/46 (2006.01) C07D 307/52 (2006.01)

Patent

CA 1303048

ABSTRACT The present invention is novel diarylalkanoids having activity as lipoxygenase inhibitors, novel pharmaceutical compositions therefor, and novel methods of use in treating asthma, allergies, cardiovascular diseases, migraines, psoriasis and immunoinflammatory diseases for diarylalkanoids. The compounds of this invention are also useful as cytoprotective agents. The compounds have the general formula: Image wherein R1, R2, T, X, Y, Z and Ar are as defined in the disclosure and claims.

532053

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