Diarylamine-containing compounds and compositions, and their...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/14 (2006.01) A61K 31/502 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2603250

Described herein are compounds that include a diarylamine structural feature. Also described herein are methods for making such compounds, methods for using such compounds to modulate the activity of steroid hormone nuclear receptors, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent diseases or conditions associated with the activity of steroid hormone nuclear receptors.

L'invention concerne des composés comprenant un élément structurel diarylamine. L'invention se rapporte également à des procédés de fabrication desdits composés, à des procédés d'utilisation des composés pour moduler l'activité des récepteurs nucléaires des hormones stéroïdes, et à des compositions pharmaceutiques et des médicaments renfermant lesdits composés. L'invention porte aussi sur des procédés d'utilisation des composés, compositions pharmaceutiques et médicaments précités pour traiter et/ou prévenir des maladies et états associés à l'activité des récepteurs nucléaires des hormones stéroïdes.

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