C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/86 (2006.01) A61K 31/4166 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2703635
The present invention relates to diarylhydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer, wherein R3 is selected from the group consisting of hydrogen, cyano, formyl, wherein R1 and R2 together comprise eight or fewer carbon atoms and are, selected from the group consisting of alkyl substitated alkyl and, together with the carbon Lo with they are linked, a cyckoalkyl or substituted cyeloalkyl group,
L'invention porte sur des composés de diarylhydantoïne, leur procédé de synthèse et leur utilisation dans le traitement du cancer de la prostate réfractaire à l'hormonothérapie.
Jung Michael E.
Sawyers Charles L.
Tran Chris
Yoo Dongwon
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Regents Of The University Of California
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