Diarylsulfones as 5-ht2a antagonists

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 317/44 (2006.01) A61K 31/10 (2006.01) A61K 31/277 (2006.01) A61K 31/397 (2006.01) A61K 31/4164 (2006.01) A61K 31/4196 (2006.01) C07D 205/04 (2006.01) C07D 207/10 (2006.01) C07D 211/38 (2006.01) C07D 213/71 (2006.01) C07D 233/64 (2006.01) C07D 241/08 (2006.01) C07D 249/08 (2006.01) C07D 271/10 (2006.01) C07D 295/096 (2006.01)

Patent

CA 2577837

Compounds of formula (I) are potent and selective antagonists of the human 5- HT2A receptor, and hence useful in treatment of a variety of adverse conditions of the CNS.

La présente invention décrit des composés de formule I : I qui sont des antagonistes puissants et sélectifs du récepteur humain 5-HT2A, et qui peuvent à ce titre être employés dans le traitement de nombreuses maladies du SNC.

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