Diastereoisomer a of 2,6-dimethyl-4-(3-nitrophenyl)-1,...

Details Diastereoisomer a of 2,6-dimethyl-4-(3-nitrophenyl)-1,... Diastereoisomer a of 2,6-dimethyl-4-(3-nitrophenyl)-1,...

C - Chemistry, Metallurgy

07

D

167/231, 260/279

C07D 401/12 (2006.01) A61K 31/44 (2006.01) C07D 207/24 (2006.01) C07D 211/90 (2006.01)

Patent

CA 1273930

ABSTRACT OF THE DISCLOSURE This invention relates to diastereoisomer A of 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5- dicarboxylic acid 3-(1-benzylpyrrolidin-3-yl)ester 5-methyl ester, dextro-rotatory optical isomer thereof, and the pharmaceutically acceptable acid addition salts thereof. The invention further relates to a process of producing these compounds and also to medicaments using these compounds as an effective component. The compounds of this invention have a vasodilating activity and a hypotensive activity.

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