Diastereomeric 5r,6s-6-(1r-hydroxyethyl)-2-(cis-1-oxo-...

Details Diastereomeric 5r,6s-6-(1r-hydroxyethyl)-2-(cis-1-oxo-... Diastereomeric 5r,6s-6-(1r-hydroxyethyl)-2-(cis-1-oxo-...

C - Chemistry, Metallurgy

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C07D 499/87 (2006.01) A61K 31/43 (2006.01) C07D 303/16 (2006.01) C07D 333/28 (2006.01) C07D 333/32 (2006.01) C07D 333/34 (2006.01) C07D 333/48 (2006.01) C07D 409/12 (2006.01) C07D 499/88 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1338830

Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(1S-oxo- 3R-thiolanylthio)-2-penem-3-carboxylic acid and 5R,6S- 6-(1R-hydroxyethyl)-2-(1R-oxo-3S-thiolanylthio)-2--penem- 3-carboxylic acid, and pharmaceutically-acceptable salts and in vivo hydrolyzable esters thereof, useful as systemic antibacterial agents; and intermediates and processes which are useful in the said synthesis of said diastereoisomers.

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