C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/4188 (2006.01) A61K 31/427 (2006.01) C07D 277/34 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2554217
The present invention relates to certain derivatives of cycloalkanediones invariably substituted with a chroman-2-yl, 2-quinolyl or -O-phenyl residue which are serotonin (5-hydroxytryptamine, 5-HT) 5-HT1A receptor subtype agonists modulators, to their stereochemical isomers and to their use in the preparation of a medicament for the treatment of pathological states for which an agonist a modulator of these receptors is indicated.
L'invention concerne certains dérivés de cycloalcanediones invariablement substitués par un résidu chroman-2-yl, 2-quinolyle or -O-phényle, qui sont des modulateurs agonistes du sous-type (5-hydroxytryptamine, 5-HT) 5-HT¿1A? des récepteurs de la sérotonine, ainsi que leurs isomères stéréochimiques, et leur utilisation pour la préparation d'un médicament destiné au traitement d'états pathologiques pour lesquels un modulateur ou agoniste de ces récepteurs est indiqué.
Benhamu Salama Bellinda
Del Rio Zambrana Joaquin
Frechilla Manso Diana
Lopez Rodriguez Maria Luz
Marco Martinez Isabel
Cepa Schwarz Pharma S.l.
Goudreau Gage Dubuc
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