Diazabicyclic compounds useful in the treatment of cns and...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/08 (2006.01) A61K 31/4995 (2006.01)

Patent

CA 2498291

The present invention relates to a compounds of formula (I): wherein A, B, D, E and F are defined herein; that are useful in treating central nervous system (CNS) diseases, disorders and conditions, such as but not limited to nicotine addiction, schizophrenia, depression, Alzheimer's disease, Parkinson's disease and ADHD. The present invention further comprises pharmaceutical compositions containing such compounds and methods of treatment comprising the use of such compounds.

La présente invention concerne des composés de formule I, dans laquelle A, B, D, E et F sont tels que définis dans la description. Ces composés s'utilisent dans le traitement de maladies, troubles et pathologies associés au système nerveux central (SNC), tels que notamment pas pas exclusivement la dépendance à la nicotine, la schizophrénie, la dépression, la maladie d'Alzheimer, la maladie de Parkinson et le THADA. Cette invention concerne également des compositions pharmaceutiques contenant lesdits composés ainsi que des méthodes de traitement fondées sur l'utilisation de ces composés.

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