Diazabicyclo (2,2,2) octadiones and process for their...

Details Diazabicyclo (2,2,2) octadiones and process for their... Diazabicyclo (2,2,2) octadiones and process for their...

C - Chemistry, Metallurgy

07

D

260/242.5

C07D 471/08 (2006.01)

Patent

CA 1209996

Abstract Disclosed are diazabicyclo (2,2,2,) octadiones having the formula: Image I wherein R1-R6 are independently selected from the group consisting of hydrogen, methyl, and ethyl, which are prepared by: A. reacting a compound having the formula: Image II wherein R and R' are independently selected from the group con- sisting of hydrogen and alkyl or cyclo alkyl having 1 to 10 carbon atoms, and R1-R6 are independently selected from the group consis- ting of hydrogen, methyl, and ethyl, with B. a reactant selected from the group consisting of ammonia and primary amines having the formula R2-NH2 wherein R2 is selected from the group consisting of hydrogen, methyl, and ethyl, The compounds of formula I are useful in preparing the correspon- ding octanes which are in turn useful as inter alia antihistamines, sedatives and antibiotics.

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