Diazacycloalkanes as oxytocin agonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 495/04 (2006.01) A61K 31/495 (2006.01) A61P 15/04 (2006.01) A61P 15/10 (2006.01) C07D 209/00 (2006.01) C07D 223/00 (2006.01) C07D 231/00 (2006.01) C07D 243/00 (2006.01) C07D 333/00 (2006.01) C07D 471/14 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2453962

Compounds according to general formula (1), wherein G1 is NR5R6 or a fused polycyclic group are novel. They are selective and potent oxytocin agonists. Pharmaceutical compositions of such compounds are useful in the treatment of, inter alia, erectile dysfunction.

L'invention concerne des nouveaux composés de formule générale (1), dans laquelle G?1¿ désigne NR?5¿R?6¿ ou un groupe polycyclique fusionné. Ces composés sont des agonistes de l'ocytocine sélectifs et puissants. L'invention concerne également des compositions pharmaceutiques de tels composés qui sont utiles notamment dans le traitement du dysfonctionnement érectile.

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