C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/10 (2006.01) A61K 31/437 (2006.01) A61K 31/4375 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2620124
The present invention is directed to diazaspirodecane compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
L'invention concerne des composés de diazaspirodécane qui sont des antagonistes des récepteurs d'orexine, et qui sont utilisés dans le traitement ou la prévention de troubles et de maladies neurologiques et psychiatriques dans lesquels sont impliqués des récepteurs d'orexine. L'invention concerne également des compositions pharmaceutiques comprenant ces composés, ainsi que l'utilisation de ces composés et de ces compositions dans la prévention ou le traitement de maladies dans lesquelles sont impliqués des récepteurs d'orexine.
Breslin Michael J.
Cox Christopher D.
Whitman David B.
Merck And Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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