C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/06 (2006.01) A61K 31/55 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2220407
Diazepino-indoles of formula (I), wherein A is mono- to trisubstituted aryl or heteroaryl, and B is an -OR1 or -NR2R3 group where R1, R2 and R3 are particularly hydrogen, and racemic forms, enantiomers and pharmaceutically acceptable salts thereof, as phosphodiesterase IV inhibitors, are disclosed.
Diazépino-indoles de formule (I) dans laquelle A est aryle ou hétéroaryle mono- à trisubstitué, B est un groupe -OR1 ou -NR2R3, où R1, R2, R3 sont notamment hydrogènes, leurs formes racémiques, leurs énantiomères, et leurs sels pharmaceutiquement acceptables; qui sont inhibiteurs de phosphodiestérases 4.
Calvet Alain
Dahl Svein G.
Jacobelli Henry
Pascal Yves
Payne Adrian
Institut de Recherche Jouveinal
Robic
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