Diazepino-indoles as phosphodiesterase iv inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/06 (2006.01) A61K 31/55 (2006.01) A61K 31/5517 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2200628

The use of diazepino-indole derivatives of formula (I), wherein R is hydrogen, lower alkyl or lower alkoxy, and A is mono- to trisubstituted aryl or heteroaryl, and racemic forms, enantiomers and pharmaceutically acceptable salts thereof, containing novel products, for preparing drugs useful for treating disorders requiring therapy using phosphodiesterase IV inhibitors.

Application de dérivés de diazépino-indoles de formule (I), dans laquelle: R est hydrogène, alkyle inférieur, alcoxy inférieur; A est aryle ou hétéroaryle mono- à tribsubstitué, leurs formes racémiques, leur énantiomères, et leurs sels pharmaceutiquement acceptables, qui comprennent de nouveaux produits, pour la préparation de médicaments destinés au traitement des affections relevant d'une thérapie par les inhibiteurs de phosphodiestérases IV.

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