Diazole and tetrazole derivatives of...

C - Chemistry – Metallurgy – 07 – D

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C07D 501/36 (2006.01) A23K 1/17 (2006.01) A61D 7/00 (2006.01) A61K 31/43 (2006.01) A61K 31/545 (2006.01) A61K 31/695 (2006.01) C07D 501/04 (2006.01) C07D 501/60 (2006.01)

Patent

CA 1088519

ABSTRACT New diazole and tetrazolo derivatives of cyano- methylthioacetylcephalosporins of the following general formula, and their salts Image wherein R is hydrogen, lower alkyl, aralkyl, tri(lower alkyl)-silyl, a salt forming ion or the group Image ; R1, R2, R3 and R5 each is hydrogen or lower alkyl; R4 is lower alkyl, aryl or aralkyl; Y is oxygen, sulfur or nitro- gen; m is 2 or 3 and N is 0 or 1, the sum of m and n being 3; are useful as antibacterial agents.

211083

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