Dibenz[b,f][1,4]oxazepin-11(10h)-ones for multidrug...

Details Dibenz[b,f][1,4]oxazepin-11(10h)-ones for multidrug... Dibenz[b,f][1,4]oxazepin-11(10h)-ones for multidrug...

C - Chemistry, Metallurgy

07

D

C07D 267/20 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2075861

This invention relates to a compound of formula I (see formula I) wherein p is 1 to 3; R1 and R2 each are independently hydrogen or an acyl group R6CO-, in which R6 is C1-6 alkyl, C3-7 cycloalkyl, C2-7 alkenyl, aryl or radical of the formula (see formula II) R3 is hydrogen or chloro; R4 and R5 each are independently C1-6 alkyl. Compounds of formula I are useful for the reversal of multidrug resistance of cancer drugs.

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