Dibenz¬cd,f|indole derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 209/90 (2006.01) A61K 31/40 (2006.01) C07D 209/80 (2006.01)

Patent

CA 2206519

1-Alkyl-9,10-dihydroxy-4,5,5a,6-tetrahydro-dibenz[cd,f]indoles of formula (I) may be used in the treatment of Morbus Parkinson, alcohol abuse and drug dependency. In said formula, R1, R2 and R3 are independently (C1-4)alkyl, in free or acid addition salt form.

Des 1-alkyl-9,10-dihydroxy-4,5,5a,6-tétrahydro-dibenz[cd,f]indoles peuvent être utilisés dans le traitement de la maladie de Parkinson, l'abus d'alcool et la pharmacodépendance. Dans la formule, R¿1?, R¿2? et R¿3? représentent, indépendamment l'un de l'autre, alkyle en C¿1-4? sous forme libre ou de sel d'addition d'acide.

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