C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 313/12 (2006.01) A61K 31/335 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2608889
The present invention relates to compounds of formula (I), in which R1, R2, R3, R4, X and Y have the meanings indicated in the description. These compounds have immuno-modulating effects, as well as an inhibiting or regulating effect on the release of IL-1.beta. and/or TNF-.alpha.. They can therefore be used for the treatment of diseases associated with a disturbance of the immune system.
La présente invention concerne des composés de formule (I), dans laquelle R1, R2, R3, R4, X et Y ont les significations indiquées dans la description. Ces composés possèdent une action immunomodulatrice et un effet d'inhibition ou de régulation de la libération de IL-1ß et/ou TNF-a. Ils peuvent donc être utilisés pour traiter des maladies liées à un trouble du système immunitaire.
Albrecht Wolfgang
Greim Cornelia
Laufer Stefan
Striegel Hans-Guenter
Tollmann Karola
Deeth Williams Wall Llp
Merckle Gmbh
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