Dibenzodiazepinone analogues, processes for their production...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 243/38 (2006.01) A61K 31/5513 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2511750

This invention relates to novel dibenzodiazepinone analogs, and to pharmaceutically acceptable salts, solvates and prodrugs, to pharmaceutical compositions comprising them, and to methods for obtaining such compounds. One method of obtaining the dibenzodiazepinone analogs is by post-biosynthesis chemical modifications of the farnesyl dibenzodiazepinone ECO-4601. The dibenzodiazepinone analogs are useful as pharmaceuticals, in particular as antineoplastic agents.

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