C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/241.1, 260/2
C07D 487/04 (2006.01) C07D 223/20 (2006.01) C07D 267/20 (2006.01) C07D 281/16 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)
Patent
CA 1150253
ABSTRACT The invention relates to compounds of formula I Image (I) [wherein R1, R2, R3 and R4, which may be the same or different, each represents a hydrogen or halogen atom or a C1 to C6 alkyl or C1 to C6 alkoxy group; R5 and R6, which may be the same or different, each represents a hydrogen atom or a C1 to C6 alkyl or C3 to C6 alkenyl group; or R5 and R6, together with the nitrogen atom to which they are attached, represent a pyrrolidino, piperidino or morpholino group; and X represents an oxygen or sulfur atom or a methylene group] and the tautomeric forms (where R6 represents a hydrogen atom) of formula Ia Image (Ia) as well as to acid adition salts of compounds of formulae I and Ia and processes for their preparation. The compounds of formulae I and Ia and their physiolo- gically acceptable acid addition salts possess anti- allergic, antihistaminic and antiserotonic activity and the invention also releates to pharmaceutical preparations containing these compounds or salts.
372485
Fugner Armin
Schneider Claus
Walther Gerhard
Weber Karl-Heinz
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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