Dibenzoxazepine derivative, process for preparing the same,...

C - Chemistry – Metallurgy – 07 – D

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204/91.17, 260/2

C07D 267/02 (2006.01) B01J 19/08 (2006.01) C07D 267/20 (2006.01) C08F 2/46 (2006.01) C08J 3/28 (2006.01) C08J 7/18 (2006.01)

Patent

CA 1162189

ABSTRACT OF THE DISCLOSURE Dibenzoxazepine derivatives of the formula: Image wherein R1 is a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxyl group: n is an integer of 1 or 2 provided that each R1 may be different when n is 2; R2 is a hydrogen atom or a lower alkyl group, R3 is a hydrogen atom, a lower alkyl group, a phenyl group which may have a m-CH3 group as substituent or a styryl group, process for preparing the same and pharmaceutical composi- tion containing the same are disclosed. The compounds of the formula have lipid lowering activity, lipid peroxide low- ering activity, blood sugar lowering activity and activity to inhibit the aggregation of platelets, and hence are useful as a medicine.

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