C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/18 (2006.01)
Patent
CA 2543079
Novel dicationic, heterocyclic triaryl compounds are useful in the treatment of microbial infections, such as Trypanosoma brucei rhodesiense infection and Plasmodium falciparum infection. These compounds are accordingly useful in treating second-stage human African trypanosomiasis. Pharmaceutical formulations comprising these compounds can be used in methods of treating microbial infections.
L'invention concerne de nouveaux composés triaryl hétérocyliques dicationiques qui peuvent être utilisés pour traiter des infections microbiennes, telles qu'une infection par Trypanosoma brucei rhodesiense ou une infection par Plasmodium falciparum. Ces composés peuvent par conséquent servir à traiter une trypanosomiase africaine humaine au deuxième stade. Cette invention se rapporte en outre à des formulations pharmaceutiques qui renferment lesdits composés et peuvent être utilisées au cours de procédés pour traiter des infections microbiennes.
Boykin David W.
Brun Reto
Ismail Mohamed A.
Tidwell Richard R.
Wilson W. David
Brun Reto
Georgia State University Research Foundation Inc.
Norton Rose Or S.e.n.c.r.l.,s.r.l./llp
University Of North Carolina At Chapel Hill
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