Dicer substrate rna peptide conjugates and methods for rna...

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A61K 47/48 (2006.01) C12N 15/113 (2010.01) A61K 31/713 (2006.01) A61P 31/16 (2006.01)

Patent

CA 2661093

Dicer substrate RNA peptide conjugates comprising a double stranded ribonucleic acid (dsRNA) having a sense strand and an antisense strand, and a peptide, wherein the dicer substrate RNA is conjugated to the peptide, and compositions and methods of uses thereof.

La présente invention concerne des conjugués de peptide et d'ARN substrat de Dicer contenant un acide ribonucléique double brin (ARNds), lequel comporte un brin sens et un brin antisens, et un peptide, l'ARN substrat de Dicer étant conjugué au peptide, ainsi que des compositions et des procédés de leurs utilisations.

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