Diclofenac/gamma-cyclodextrin inclusion compounds

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/19 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/46 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2250009

The object of the present invention is an oral drug preparation containing the g-cyclodextrin complex of diclofenac (or pharmaceutically acceptable salts thereof, especially sodium salt) prepared by known methods and by which the gastro-intestinal irritancy of diclofenac - at the same or improved bioavailability - can be considerably decreased.

L'invention porte sur une préparation orale de médicament contenant le complexe g-cyclodextrine du diclofénac (ou ses sels pharmacocompatibles, de sodium en particulier), préparée par des techniques connues, et qui diminue considérablement l'irritation gastro-intestinale due au diclofénac, tout en en accroissant la biodisponibilité.

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