Dideoxydidehydrocarbocyclic nucleosides

Details Dideoxydidehydrocarbocyclic nucleosides Dideoxydidehydrocarbocyclic nucleosides

C - Chemistry, Metallurgy

07

D

167/220, 260/259

C07D 473/00 (2006.01) A61K 31/52 (2006.01) C07D 239/46 (2006.01) C07D 487/04 (2006.01)

Patent

CA 1339896

Disclosed are compounds of formula (see fig. I) wherein X is H, NRR1, SR, OR or halogen; Z is H, OR2 or NRR1; R,R1,R2 are H, C1-4alkyl or aryl and pharmaceutically acceptable derivatives thereof. Also disclosed are use of the compounds as antiviral and anti-tumor agents, pharmaceutical formulations, methods for the preparation of the compounds and intermediates thereto.

588614

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