Dielectric spectroscopy assays for screening of ion channel...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/02 (2006.01) C12M 1/42 (2006.01) C40B 30/10 (2006.01) G01N 27/02 (2006.01)

Patent

CA 2695216

A method for measuring membrane potential using dielectric spectroscopy is described. A new theoretical model allows for the determination of membrane potential from low-frequency impedance measurements to provide a non-evasive method which is both rapid and inexpensive.

L'invention concerne un procédé de mesure d'un potentiel de membrane utilisant une spectroscopie diélectrique. Un nouveau modèle théorique permet de déterminer un potentiel de membrane à partir de mesures d'impédance basse fréquence pour proposer un procédé non évasif qui est à la fois rapide et peu coûteux.

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