Dielectrophoretic characterisation of micro-organisms and...

G - Physics – 01 – N

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G01N 27/453 (2006.01) B03C 5/02 (2006.01) C12M 1/34 (2006.01) C12Q 1/04 (2006.01) G01N 27/447 (2006.01)

Patent

CA 2045479

Dielectrophoretic collection rates of microorganisms or other animate or inanimate dielectrically polarisable particles in suspen- sion in a fluid are established by flowing the suspension past electrodes (17, 18) energised to produce a non-uniform alternating electric field in the suspension, terminating the energi- sation of the electrodes after a predetermined time to release particles collected from the su- spension, and, downstream of the electrodes, measuring the pulse of released particles as a measure of the rate of particle collection dur- ing energisation of the electrodes. Repeated measurements at different field frequencies enable a collection-rate spectrum to be esta- blished and the particles under examination to be characterised or identified by reference to known spectra of known particles.

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