Dietary phytoestrogen in estrogen replacement therapy

A - Human Necessities – 61 – K

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A61K 31/565 (2006.01)

Patent

CA 2210811

Disclosed is a pharmaceutical composition for oral delivery. The composition includes about 1-2 mg mammalian estrogen and about 25-100 mg phytoestrogen. Compositions of the type described above are utilized, for example, in a therapeutic regimen designed to reduce the risk of coronary heart disease and osteoporosis in postmenopausal women. This method comprises the oral administration of a composition comprising a mixture of estrogen and phytoestrogen, the dosages of mammalian estrogen and phytoestrogen being about 1-2 mg, about 25-100 mg, respectively.

Préparation pharmaceutique à administration par voie orale, comportant environ 1-2 mg d'oestrogène de mammifère et environ 25-100 mg de phytoestrogènes pouvant par exemple être utilisés selon un régime thérapeutique visant à réduire les risques de maladies coronariennes et d'ostéoporose chez les femmes post ménopausées. La méthode associée comprend l'administration par voie orale d'une composition contenant un mélange d'oestrogène et de phytoestrogène de mammifère selon un dosage respectif d'environ 1 à 2 mg et d'environ 25 à 100 mg.

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