C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
167/129, 167/139
C12P 21/08 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) C12N 5/12 (2006.01) G01N 33/554 (2006.01) G01N 33/577 (2006.01)
Patent
CA 1335797
This specification discloses a purified new differentiation antigen, designated NDA3, associated with the growth and proliferation of activated B lymphocytes and characterized by a molecular weight of about 36,000 daltons. The specification also discloses an antibody capable of specifically forming a complex with purified NDA3. Another aspect of the invention provides a hybridoma which produces a monoclonal antibody that specifically recognizes the isolated NDA3. The specification also pertains to a method for detecting B cells or helper T cells, each of which has a B cell growth factor receptor, which comprises contacting a sample which contains B cells or helper T cells with substances capable of forming complexes with the B cell growth factor receptors so as to form cellular complexes between the substances and the B cell growth factor receptors, and detecting such cellular complexes.
558680
King Donald W.
Suciu-Foca Nicole
Gowling Lafleur Henderson Llp
The Trustees Of Columbia University In The City Of New York
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