Differential display protein maps

Details Differential display protein maps Differential display protein maps

G - Physics

01

N

G01N 31/00 (2006.01) G01N 27/447 (2006.01) G01N 30/02 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2446337

The present invention relates to multi-phase protein separation methods capable of resolving and characterizing large numbers of cellular proteins, including methods for efficiently facilitating the transfer of protein samples between separation phases. In particular, the present invention provides systems and methods for the generation of multi-dimensional protein maps. The present invention further provides systems and methods for the differential display of protein samples from multiple cell types. The present invention thus provides improved methods for the analysis of samples containing large numbers of proteins.

L'invention porte sur un procédé de séparation de protéines en phases multiples pouvant résoudre et caractériser un grand nombre de protéines cellulaires, sur des procédés facilitant efficacement le transfert d'échantillons de protéines entre des phases de séparation; en particulier sur des systèmes et procédés d'élaboration de cartes pluridimensionnelles de protéines; elle porte en outre sur des systèmes et procédés de présentation différentielle d'échantillons de protéines de différents types de cellules. Elle constitue donc un procédé amélioré d'analyse d'échantillons contenant un grand nombre de protéines.

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