Differential expression of markers in ovarian cancer

G - Physics – 06 – F

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G06F 15/16 (2006.01)

Patent

CA 2554703

Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.

La présente invention se rapporte à de nouveaux marqueurs du cancer de l'ovaire, qui sont à la fois sensibles et précis. Les marqueurs selon l'invention font l'objet d'une surexpression et/ou d'une expression différentielle en cas de cancer de l'ovaire, en particulier, par rapport à un tissu ovarien normal. La mesure desdits marqueurs, seuls ou combinés, dans des échantillons prélevés sur des patients, livre des informations que le diagnosticien peut mettre en corrélation avec un diagnostic probable de cancer de l'ovaire. Les marqueurs selon l'invention, seuls ou combinés, permettent d'atteindre un degré élevé de détection différentielle entre un cancer de l'ovaire et un état non cancéreux.

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