C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2649859
The present invention provides methods for systematically identifying genes and proteins and related pathways that maximize protein expression and secretion by expression profiling analysis. The present invention further provides methods for manipulating the identified genes and proteins to engineer improved cell lines.
La présente invention concerne des procédés pour identifier systématiquement des gènes, des protéines et des cheminements associés qui maximisent l'expression et la sécrétion de protéines par une analyse de profils d'expression. La présente invention concerne en outre des procédés pour manipuler les gènes et les protéines identifiés pour concevoir des lignées de cellules améliorées.
Anderson Karin
Barron Niall
Charlebois Timothy
Clynes Martin
Di Nino Dana L.
Dublin City University
Torys Llp
Wyeth
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