Differential loading of drug-eluting medical devices

A - Human Necessities – 61 – M

Patent

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A61M 31/00 (2006.01) A61K 9/00 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2728324

A medical device includes a substrate having at least one surface. The surface has a central portion and a peripheral portion. At least one bioactive agent is disposed over at least a portion of the surface. The medical device having a concentration gradient of the at least one bioactive between the central and peripheral portions.

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