Differentially expressed genes associated with her-2/neu...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 17/00 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2391805

The present invention provides human Her-2/neu overexpression modulated proteins (HOMPS) and polynucleotides encoding HOMPS polypeptides. The invention also provides HOMPS containing expression vectors and host cells, HOMPS antibodies and methods of producing HOMPS. In addition, the invention provides methods for generating, identifying and manipulating HOMPS.

La présente invention concerne des protéines humaines modulées par la surexpression de Her-2/neu (HOMPS), et des polynucléotides codant les polypeptides HOMPS. L'invention concerne également des protéines HOMPS renfermant des vecteurs d'expression et des cellules hôtes, des anticorps dirigés contre les protéines HOMPS et des méthodes de production de protéines HOMPS. En outre, l'invention concerne des méthodes permettant de générer, d'identifier et de manipuler lesdites protéines HOMPS.

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