Differentially protected orthogonal lanthionine technology

Details Differentially protected orthogonal lanthionine technology Differentially protected orthogonal lanthionine technology

C - Chemistry, Metallurgy

07

K

C07K 1/02 (2006.01) C07K 1/06 (2006.01) C07K 1/107 (2006.01) C07K 14/315 (2006.01)

Patent

CA 2756709

The present invention provides a method of synthesizing an intramolecularly bridged polypeptide comprising at least one intramolecular bridge. The present invention further provides a method of synthesizing an intramolecularly bridged polypeptide comprising two intramolecular bridges, wherein the two intramolecular bridges form two overlapping ring, two rings in series, or two embedded rings. The present invention also provides methods for synthesizing lantibiotics, including Nisin A. Additionally, the invention provides intramolecularly bridged polypeptides synthesized by the methods disclosed herein and differentially protected orthogonal lanthionines.

La présente invention porte sur un procédé de synthèse d'un polypeptide à pontage intramoléculaire comprenant au moins un pont intramoléculaire. La présente invention porte également sur un procédé de synthèse d'un polypeptide à pontage intramoléculaire comprenant deux ponts intramoléculaires, les deux ponts intramoléculaires forment deux cycles se chevauchant, deux cycles en série ou deux cycles encastrés. La présente invention porte également sur des procédés de synthèse des lantibiotiques, comprenant la Nisine A. De plus, l'invention porte sur des polypeptides à pontage intramoléculaire synthétisés par les procédés présentement décrits et protégés de façon différentielle et sur des lanthionines orthogonales protégées de façon différentielle.

Affiliated with

Also associated with

Rating

Differentially protected orthogonal lanthionine technology does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Differentially protected orthogonal lanthionine technology, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Differentially protected orthogonal lanthionine technology will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1854783