C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/06 (2006.01)
Patent
CA 2650812
The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved method for the formation of pancreatic endoderm, pancreatic hormone expressing cells and pancreatic hormone secreting cells. The present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer.
La présente invention concerne des procédés destinés à favoriser la différentiation de cellules souches pluripotentes. L'invention concerne plus particulièrement un procédé amélioré pour la formation d'endoderme pancréatique, de cellule exprimant l'hormone pancréatique, et de cellules sécrétrices d'hormone pancréatique. L'invention concerne aussi des procédés destinés à favoriser la différentiation de cellules souches pluripotentes sans utiliser de couche de cellules nourricières.
Rezania Alireza
Xu Jean
Lifescan Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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