Difluorinated piperidines for treatment of alzheimer's...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 211/34 (2006.01) A61K 31/451 (2006.01) A61K 31/454 (2006.01) A61K 31/695 (2006.01) A61P 25/28 (2006.01) C07D 401/06 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2662702

Compounds of formula (I). Selectively inhibit production of A.beta.(1-42) and hence find use in treatment of diseases associated with deposition of .beta.-amyloid in the brain.

La présente invention concerne des composés de formule (I) qui inhibent sélectivement la production de .beta.-A (1-42) et qui sont donc utilisables pour le traitement des maladies associées au dépôt de .beta.-amyloïde dans le cerveau.

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